Rabbit anti-Human Integrin-linked protein kinase 2, A197 site specific Polyclonal Antibody
Integrin-linked protein kinase 2, A197 site specific (ILK-2)
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
Integrin-linked protein kinase 2; A197 site specific; Polyclonal Antibody; A197 site specific (ILK-2); Anti -Integrin-linked protein kinase 2; anti-Integrin-linked protein kinase 2; A197 site specific antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-Integrin-linked protein kinase 2, A197 site specific antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:10-50
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:10-50
Immunogen
ILK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding A197 of human ILK2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Integrin-linked protein kinase 2, A197 site specific antibody
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.
Product Categories/Family for anti-Integrin-linked protein kinase 2, A197 site specific antibody
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Product Notes
The Integrin-linked protein kinase 2, A197 site specific (Catalog #AAA644036) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Integrin-linked protein kinase 2, A197 site specific (ILK-2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin-linked protein kinase 2, A197 site specific can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the Integrin-linked protein kinase 2, A197 site specific for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin-linked protein kinase 2, A197 site specific, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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