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Rabbit anti-Mouse Integrin alpha-L Polyclonal Antibody | anti-Itgal antibody

Rabbit anti-mouse Integrin alpha-L polyclonal Antibody

Gene Names
Itgal; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A
Reactivity
Mouse
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Integrin alpha-L; Polyclonal Antibody; Rabbit anti-mouse Integrin alpha-L polyclonal Antibody; CD11 antigen-like family member A Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; CD_antigen; Lfa-1; Ly-15; anti-Itgal antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
1163
Applicable Applications for anti-Itgal antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant mouse Integrin alpha-L protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6611
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-Itgal antibody
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Mice expressing a null mutation of the alpha-L subunit gene demonstrate impaired tumor rejection and impaired leukocytes recruitment.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
128,328 Da
NCBI Official Full Name
Integrin alpha-L
NCBI Official Synonym Full Names
integrin alpha L
NCBI Official Symbol
Itgal
NCBI Official Synonym Symbols
Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A
NCBI Protein Information
integrin alpha-L
UniProt Protein Name
Integrin alpha-L
Protein Family
UniProt Gene Name
Itgal
UniProt Synonym Gene Names
Lfa-1; Ly-15; LFA-1A; Ly-15
UniProt Entry Name
ITAL_MOUSE

Uniprot Description

ITGAL: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Belongs to the integrin alpha chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Cellular Component: cell surface; external side of plasma membrane; immunological synapse; integral to membrane; integrin complex; intercellular junction; membrane

Molecular Function: cell adhesion molecule binding; ICAM-3 receptor activity; metal ion binding; protein complex binding; protein heterodimerization activity

Biological Process: activated T cell proliferation; cell adhesion; cell surface receptor linked signal transduction; cell-cell adhesion; cell-matrix adhesion; heterophilic cell adhesion; integrin-mediated signaling pathway; leukocyte adhesion; positive regulation of calcium-mediated signaling; positive regulation of cell-cell adhesion; positive regulation of T cell proliferation; receptor clustering; regulation of cell-cell adhesion; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Research Articles on Itgal

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Product Notes

The Itgal itgal (Catalog #AAA1488250) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Integrin alpha-L polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alpha-L can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Itgal itgal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alpha-L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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