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Goat anti-Human Insulysin Polyclonal Antibody | anti-CMU_002640 antibody

Insulysin (IDE, insulin-degrading enzyme, FLJ35968, Insulinase, Insulin-degrading Enzyme, Insulin Protease)

Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by affinity chromatography.
Synonyms
Insulysin; Polyclonal Antibody; Insulysin (IDE; insulin-degrading enzyme; FLJ35968; Insulinase; Insulin-degrading Enzyme; Insulin Protease); Anti -Insulysin (IDE; anti-CMU_002640 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Insulysin at ~120kD. Species sequence homology: canine.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Applicable Applications for anti-CMU_002640 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml
Immunogen
Synthetic peptide, C-QQYNFDRDNTE, from the internal region of human Insulysin.
Positive Control
Lysates of cell line K562
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 monthsat -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-CMU_002640 antibody
Insulysin, a wide expressed protein, is responsible for the degradation of insulin in cells. Primarily located in the cytosol, insulysin has been isolated from many different tissues and cell lines, and can degrade intact insulin, insulin B-chain, glucagon, denatured hemoglobin, alpha-amyloid protein, TGF-alpha and amylin. Recent work implicates insulysin in clearing beta amyloid plaques from the brain, and has generated much interest in Alzheimer's disease research.
Product Categories/Family for anti-CMU_002640 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
insulysin
NCBI Official Symbol
CMU_002640
NCBI Protein Information
insulysin

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Product Notes

The CMU_002640 (Catalog #AAA620089) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Insulysin (IDE, insulin-degrading enzyme, FLJ35968, Insulinase, Insulin-degrading Enzyme, Insulin Protease) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Insulysin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml. Researchers should empirically determine the suitability of the CMU_002640 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insulysin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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