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Western Blot (WB) (INHBE rabbit polyclonal antibody. Western Blot analysis of INHBE expression in human liver.)

Rabbit anti-Human, Mouse INHBE Polyclonal Antibody | anti-INHBE antibody

INHBE (Inhibin beta E Chain, Activin beta-E Chain, MGC4638)

Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
INHBE; Polyclonal Antibody; INHBE (Inhibin beta E Chain; Activin beta-E Chain; MGC4638); Anti -INHBE (Inhibin beta E Chain; anti-INHBE antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human INHBE. Species Crossreactivity: mouse.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHHLYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
Applicable Applications for anti-INHBE antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human INHBE, aa1-350 (NP_113667.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(INHBE rabbit polyclonal antibody. Western Blot analysis of INHBE expression in human liver.)

Western Blot (WB) (INHBE rabbit polyclonal antibody. Western Blot analysis of INHBE expression in human liver.)

Western Blot (WB)

(INHBE rabbit polyclonal antibody. Western Blot analysis of INHBE expression in mouse liver.)

Western Blot (WB) (INHBE rabbit polyclonal antibody. Western Blot analysis of INHBE expression in mouse liver.)

Western Blot (WB)

(Western Blot analysis of INHBE expression in transfected 293T cell line by INHBE polyclonal antibody. Lane 1: INHBE transfected lysate (38.6kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of INHBE expression in transfected 293T cell line by INHBE polyclonal antibody. Lane 1: INHBE transfected lysate (38.6kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-INHBE antibody
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Product Categories/Family for anti-INHBE antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,561 Da
NCBI Official Full Name
inhibin beta E chain
NCBI Official Synonym Full Names
inhibin, beta E
NCBI Official Symbol
INHBE
NCBI Protein Information
inhibin beta E chain; activin beta E; activin beta-E chain
UniProt Protein Name
Inhibin beta E chain
Protein Family
UniProt Gene Name
INHBE
UniProt Entry Name
INHBE_HUMAN

NCBI Description

INHBE is a member of the activin beta family (see INHBA; MIM 147290) that plays a role in pancreatic exocrine cell growth and proliferation (Hashimoto et al., 2006 [PubMed 16426570]).[supplied by OMIM, May 2008]

Uniprot Description

INHBE: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: extracellular space

Molecular Function: growth factor activity; hormone activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; regulation of MAPKKK cascade; cell development; growth

Research Articles on INHBE

Similar Products

Product Notes

The INHBE inhbe (Catalog #AAA641582) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INHBE (Inhibin beta E Chain, Activin beta-E Chain, MGC4638) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's INHBE can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the INHBE inhbe for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRLPDVQLWL VLLWALVRAQ GTGSVCPSCG GSKLAPQAER ALVLELAKQQ ILDGLHLTSR PRITHPPPQA ALTRALRRLQ PGSVAPGNGE EVISFATVTD STSAYSSLLT FHLSTPRSHH LYHARLWLHV LPTLPGTLCL RIFRWGPRRR RQGSRTLLAE HHITNLGWHT LTLPSSGLRG EKSGVLKLQL DCRPLEGNST VTGQPRRLLD TAGHQQPFLE LKIRANEPGA GRARRRTPTC EPATPLCCRR DHYVDFQELG WRDWILQPEG YQLNYCSGQC PPHLAGSPGI AASFHSAVFS LLKANNPWPA STSCCVPTAR RPLSLLYLDH NGNVVKTDVP DMVVEACGCS. It is sometimes possible for the material contained within the vial of "INHBE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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