Rabbit ILEI / FAM3C Polyclonal Antibody | anti-ILEI antibody

Rabbit Polyclonal to Human ILEI / FAM3C

Cat. Num. AAA241682

• Gene Names: FAM3C; ILEI; GS3786
• Reactivity: Bovine, Chimpanzee, Chicken, Dog, Human, Monkey, Mouse, Opossum, Pufferfish, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: ILEI / FAM3C; Polyclonal Antibody; Rabbit Polyclonal to Human ILEI / FAM3C; Anti-ILEI / FAM3C Antibody (aa40-80) IHC-plus; FAM3C; GS3876; GS3786; Interleukin-like EMT inducer; Predicted osteoblast protein; ILEI; Protein FAM3C; Human ILEI; anti-ILEI antibody

• Host: Rabbit
• Reactivity: Bovine, Chimpanzee, Chicken, Dog, Human, Monkey, Mouse, Opossum, Pufferfish, Rat
• Clonality: Polyclonal
• Specificity: A portion of amino acids 40-80 of human FAM3C
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.05% BSA, 0.05% sodium azide.
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 227

• Applicable Applications for anti-ILEI antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 - 10 ug/ml), WB (0.5 - 1 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human FAM3C.
• Immunogen Type: Synthetic peptide
• Immunogen: ILEI / FAM3C antibody was raised against synthetic peptide from human FAM3C.
• Antigen Modification: aa40-80
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-FAM3C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of human FAM3C in human brain lysate (0.5 ug/ml) 1) absence, 2) presence of immunizing peptide, 3) mouse brain lysate (0.5 ug/ml), and 4) in rat brain lysate (0.5 ug/ml) using antibody)

NCBI and Uniprot Product Information

• NCBI GI #: 7661714
• NCBI GeneID: 10447
• NCBI Accession #: NP_055703.1
• NCBI GenBank Nucleotide #: NM_014888.2
• UniProt Accession #: Q92520; A6NDN2; A8K3R7
• Molecular Weight: 24,680 Da
• NCBI Official Full Name: protein FAM3C
• NCBI Official Synonym Full Names: family with sequence similarity 3, member C
• NCBI Official Symbol: FAM3C
• NCBI Official Synonym Symbols: ILEI; GS3786
• NCBI Protein Information: protein FAM3C; interleukin-like EMT inducer; predicted osteoblast protein; interleukin-like epithelial-mesenchymal transition inducer
• UniProt Protein Name: Protein FAM3C
• UniProt Gene Name: FAM3C
• UniProt Synonym Gene Names: ILEI
• UniProt Entry Name: FAM3C_HUMAN

NCBI Description

This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. [provided by RefSeq, Mar 2010]

Uniprot Description

FAM3C: May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. Belongs to the FAM3 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: Golgi apparatus; cytoplasmic membrane-bound vesicle; extracellular region

Molecular Function: cytokine activity

Biological Process: multicellular organismal development