Rabbit anti-Human, Rat IL9 Polyclonal Antibody | anti-IL9 antibody

IL9 Polyclonal Antibody

Cat. Num. AAA3011247

• Gene Names: IL9; P40; HP40; IL-9
• Reactivity: Human, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: IL9; Polyclonal Antibody; IL9 Polyclonal Antibody; Cytokine P40; Homolog of mouse T cell and mast cell growth factor 40; HP40; IL 9; IL-9; Il9; IL9_HUMAN; Interleukin 9; Interleukin-9; Mast cell growth factor; MCGF; Megakaryoblast growth factor; P40; p40 cytokine; p40 T cell and mast cell growth factor; T cell growth factor 3; T cell growth factor p40; T-cell growth factor P40; TCGF 3; anti-IL9 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: IL9 polyclonal antibody detects endogenous levels of IL9 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 144

• Applicable Applications for anti-IL9 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant full length Human IL9.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat lung using IL9 antibody. |Immunohistochemistry of paraffin-embedded human colon cancer using IL9 antibody.)

Related Product Information for anti-IL9 antibody

Interleukin-9, or IL-9, is a TH2 cytokine that has been shown to promote the antigen-independent growth of some T helper clones. IL-9 is a pleiotropic cytokine with multiple functions on cells of lymphoid, myeloid and mast cell lineages. Both mouse and human cDNAs encode 144 amino acid precursors with 18 amino acid residue signal peptides that are cleaved to form the mature biologically active glycoprotein. Although IL-9 is constitutively expressed in vitro by several transformed T cell lines, IL-9 expression can be induced in human peripheral blood T lymphocytes by T cell activators such as phorbol esters (PHA) and anti-CD3 antibodies. IL-9 exerts its biological effects through the interleukin-9 receptor, IL-9R. IL-9R is composed of at least two subunits: t

NCBI and Uniprot Product Information

• NCBI GI #: 10834980
• NCBI GeneID: 3578
• NCBI Accession #: NP_000581.1
• NCBI GenBank Nucleotide #: NP_000581.1
• UniProt Accession #: P15248
• NCBI Official Full Name: interleukin-9
• NCBI Official Synonym Full Names: interleukin 9
• NCBI Official Symbol: IL9
• NCBI Official Synonym Symbols: P40; HP40; IL-9
• NCBI Protein Information: interleukin-9
• UniProt Protein Name: Interleukin-9
• Protein Family: Interleukin
• UniProt Gene Name: IL9
• UniProt Synonym Gene Names: IL-9
• UniProt Entry Name: IL9_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]

Uniprot Description

IL9: Supports IL-2 independent and IL-4 independent growth of helper T-cells. Belongs to the IL-7/IL-9 family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; interleukin-9 receptor binding; cytokine activity

Biological Process: positive regulation of cell proliferation; immune response; inflammatory response; positive regulation of cell growth; positive regulation of interleukin-5 biosynthetic process