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Western Blot (WB) (Western blot analysis of anti-IL3R Pab (RB06990) in HL60 cell line lysates (35ug/lane). IL3R (arrow) was detected using the purified Pab.)

Rabbit anti-Human IL3R Polyclonal Antibody | anti-CSF2RB antibody

IL3R Antibody (C-term V759)

Gene Names
CSF2RB; CD131; IL3RB; IL5RB; SMDP5; CDw131
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
IL3R; Polyclonal Antibody; IL3R Antibody (C-term V759); Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; CSF2RB; IL3RB; IL5RB; anti-CSF2RB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This IL3R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-773 amino acids from the C-terminal region of human IL3R.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.43 (varies by lot)
Sequence Positions
744-773
Sequence Length
897
Applicable Applications for anti-CSF2RB antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of anti-IL3R Pab (RB06990) in HL60 cell line lysates (35ug/lane). IL3R (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-IL3R Pab (RB06990) in HL60 cell line lysates (35ug/lane). IL3R (arrow) was detected using the purified Pab.)
Related Product Information for anti-CSF2RB antibody
Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Product Categories/Family for anti-CSF2RB antibody
References
Murphy, J.M., et al., J. Biol. Chem. 279(25):26500-26508 (2004).
McClure, B.J., et al., Blood 101(4):1308-1315 (2003).
Scibek, J.J., et al., Anal. Biochem. 307(2):258-265 (2002).
Blake, T.J., et al., J. Leukoc. Biol. 72(6):1246-1255 (2002).
Evans, C.A., et al., Blood 100(9):3164-3174 (2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97336
NCBI Official Full Name
cytokine receptor common subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
CSF2RB
NCBI Official Synonym Symbols
CD131; IL3RB; IL5RB; SMDP5; CDw131
NCBI Protein Information
cytokine receptor common subunit beta
UniProt Protein Name
Cytokine receptor common subunit beta
Protein Family
UniProt Gene Name
CSF2RB
UniProt Synonym Gene Names
IL3RB; IL5RB
UniProt Entry Name
IL3RB_HUMAN

NCBI Description

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

Uniprot Description

CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; interleukin-5 receptor activity; interleukin-3 receptor activity; receptor activity

Biological Process: response to lipopolysaccharide; respiratory gaseous exchange; signal transduction

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5

Research Articles on CSF2RB

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Product Notes

The CSF2RB csf2rb (Catalog #AAA9214008) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 744-773. The IL3R Antibody (C-term V759) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL3R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CSF2RB csf2rb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL3R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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