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Western Blot (WB) (Western blot analysis of extract of various cells, using IL27RA antibody.)

Rabbit anti-Human IL27RA Polyclonal Antibody | anti-IL27RA antibody

IL27RA Polyclonal Antibody

Gene Names
IL27RA; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
Reactivity
Human
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
IL27RA; Polyclonal Antibody; IL27RA Polyclonal Antibody; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; anti-IL27RA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Sequence Length
636
Applicable Applications for anti-IL27RA antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of human IL27RA
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47066 / sc-99083
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extract of various cells, using IL27RA antibody.)

Western Blot (WB) (Western blot analysis of extract of various cells, using IL27RA antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69kDa
NCBI Official Full Name
interleukin-27 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 27 receptor subunit alpha
NCBI Official Symbol
IL27RA
NCBI Official Synonym Symbols
CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
NCBI Protein Information
interleukin-27 receptor subunit alpha
UniProt Protein Name
Interleukin-27 receptor subunit alpha
Protein Family
UniProt Gene Name
IL27RA
UniProt Synonym Gene Names
CRL1; TCCR; WSX1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; TCCR
UniProt Entry Name
I27RA_HUMAN

NCBI Description

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]

Uniprot Description

IL27RA: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1- type immune responses. Also appears to be involved in innate defense mechanisms. Belongs to the type I cytokine receptor family. Type 2 subfamily.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; immune response

Research Articles on IL27RA

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Product Notes

The IL27RA il27ra (Catalog #AAA2541481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL27RA Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL27RA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the IL27RA il27ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL27RA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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