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Western Blot (WB) (Anti-IL21R Antibody (N-Term) at 1:2000 dilution + A2058 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 59 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human IL21R Polyclonal Antibody | anti-IL21R antibody

IL21R Antibody (N-Term)

Gene Names
IL21R; NILR; CD360
Reactivity
Human
Applications
Western Blot
Synonyms
IL21R; Polyclonal Antibody; IL21R Antibody (N-Term); Purified Rabbit Polyclonal Antibody (Pab); Interleukin-21 receptor; IL-21 receptor; IL-21R; Novel interleukin receptor; CD360; NILR; anti-IL21R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Specificity
This IL21R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 131-165 amino acids from human IL21R.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
538
Applicable Applications for anti-IL21R antibody
Western Blot (WB)
Application Notes
WB ~~ 1:2000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-IL21R Antibody (N-Term) at 1:2000 dilution + A2058 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 59 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-IL21R Antibody (N-Term) at 1:2000 dilution + A2058 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 59 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-IL21R antibody
This is a receptor for interleukin-21.
Product Categories/Family for anti-IL21R antibody
References
Parrish-Novak J.,et al.Nature 408:57-63(2000). Ozaki K.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:11439-11444(2000). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59130
NCBI Official Full Name
interleukin-21 receptor isoform 1
NCBI Official Synonym Full Names
interleukin 21 receptor
NCBI Official Symbol
IL21R
NCBI Official Synonym Symbols
NILR; CD360
NCBI Protein Information
interleukin-21 receptor
UniProt Protein Name
Interleukin-21 receptor
Protein Family
UniProt Gene Name
IL21R
UniProt Synonym Gene Names
NILR; IL-21 receptor; IL-21R
UniProt Entry Name
IL21R_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

Uniprot Description

IL21R: This is a receptor for interleukin-21

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11

Cellular Component: integral to membrane

Molecular Function: interleukin-21 receptor activity

Biological Process: natural killer cell activation

Disease: Ige Responsiveness, Atopic; Il21r Immunodeficiency

Research Articles on IL21R

Similar Products

Product Notes

The IL21R il21r (Catalog #AAA9215794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL21R Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL21R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:2000. Researchers should empirically determine the suitability of the IL21R il21r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL21R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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