Western Blot (WB)
(Western Blot (WB) analysis of IL17D polyclonal antibody at 1:500 dilutionLine1:Hela whole cell lysate)
Rabbit anti-Human IL17D Polyclonal Antibody | anti-IL17D antibody
IL17D Polyclonal Antibody
Gene Names
IL17D; IL-17D
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
IL17D; Polyclonal Antibody; IL17D Polyclonal Antibody; Interleukin-17D; IL-17D; Interleukin-27; IL-27; IL27; anti-IL17D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
IL17D polyclonal antibody detects endogenous levels of IL17D protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
202
Applicable Applications for anti-IL17D antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human IL17D.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of IL17D polyclonal antibody at 1:500 dilutionLine1:Hela whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of IL17D polyclonal antibody at 1:500 dilutionLine1:Hela whole cell lysate)
Related Product Information for anti-IL17D antibody
Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. The proinflammatory cytokine Interleukin 17D (IL-17D), also known as IL-27, is the largest member of the IL-17 family of cytokines. It is produced by CD4+ T cells and is predominantly expressed in brain, lung, heart, adipose tissue, pancreas and skeletal muscle. IL-17D regulates the production of other cytokines in endothelial cells, including IL-6, IL-8 and GM-CSF. It may play a role in the activation of the endothelium, which is the site of attachment for migrating immune cells. In addition, IL-17D may play a role in the amplification of a local immune response.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 22kDa
NCBI Official Full Name
interleukin-17D
NCBI Official Synonym Full Names
interleukin 17D
NCBI Official Symbol
IL17D
NCBI Official Synonym Symbols
IL-17D
NCBI Protein Information
interleukin-17D
UniProt Protein Name
Interleukin-17D
Protein Family
UniProt Gene Name
IL17D
UniProt Synonym Gene Names
IL27; IL-17D; IL-27
UniProt Entry Name
IL17D_HUMAN
NCBI Description
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
Uniprot Description
IL17D: Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells. Belongs to the IL-17 family.
Protein type: Secreted, signal peptide; Cytokine; Secreted
Chromosomal Location of Human Ortholog: 13q11
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: inflammatory response
Research Articles on IL17D
Similar Products
Product Notes
The IL17D il17d (Catalog #AAA3007164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL17D Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL17D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the IL17D il17d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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