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Rabbit IL17C1 Polyclonal Antibody | anti-IL17C1 antibody

IL17C1 Antibody Affinity Purified

Gene Names
IL17RC; CANDF9; IL17RL; IL17-RL
Reactivity
Human, Monkey
Applications
ELISA, Western Blot
Synonyms
IL17C1; Polyclonal Antibody; IL17C1 Antibody Affinity Purified; CX2; Cytokine CX2; IL 17C; IL 21; Interleukin-17C; MGC126884; MGC138401 antibody; anti-IL17C1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.80-1.1 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
791
Applicable Applications for anti-IL17C1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 70-120 on IL17RC1 protein common to C2 and C5.
Expression
Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta.
Molecular Function
interleukin-17 receptor activity
Subcellular Location
Cell membrane, Single-pass type 1 membrane protein (Note: soluble isoforms may be produced)
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-IL17C1 antibody
Affinity Purified Interleukin-17 receptor C isoform 2 precursor Antibody
Product Categories/Family for anti-IL17C1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,432 Da
NCBI Official Full Name
interleukin-17 receptor C isoform 2
NCBI Official Synonym Full Names
interleukin 17 receptor C
NCBI Official Symbol
IL17RC
NCBI Official Synonym Symbols
CANDF9; IL17RL; IL17-RL
NCBI Protein Information
interleukin-17 receptor C
UniProt Protein Name
Interleukin-17 receptor C
UniProt Gene Name
IL17RC
UniProt Synonym Gene Names
IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL
UniProt Entry Name
I17RC_HUMAN

NCBI Description

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]

Uniprot Description

IL17RC: a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3|3p25.3-p24.1

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: interleukin-17 receptor activity; receptor binding

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to fungus

Disease: Candidiasis, Familial, 9

Research Articles on IL17C1

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Product Notes

The IL17C1 il17rc (Catalog #AAA541864) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL17C1 Antibody Affinity Purified reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's IL17C1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the IL17C1 il17rc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17C1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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