Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human IL-36B Polyclonal Antibody | anti-IL36B antibody
IL-36B Antibody
Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of IL-36B in human lung tissue with IL-36B antibody at 2.5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of IL-36B in human lung tissue with IL-36B antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of IL-36B in human lung tissue with IL-36B antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of IL-36B in human lung tissue with IL-36B antibody at 20 μg/mL.)
NCBI and Uniprot Product Information
Observed: 17 kDa
NCBI Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
IL36B: Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 2q14
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-1 receptor binding; cytokine activity
Biological Process: positive regulation of T cell differentiation; cytokine and chemokine mediated signaling pathway; positive regulation of interleukin-6 production; innate immune response; immune response; inflammatory response
Research Articles on IL36B
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Product Notes
The IL36B il36b (Catalog #AAA153331) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL-36B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-36B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). IL-36B antibody can be used for detection of IL-36B by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the IL36B il36b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-36B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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