Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using IKBIP Polyclonal Antibody at dilution 1:40)
Rabbit IKBIP Polyclonal Antibody | anti-IKBIP antibody
IKBIP Polyclonal Antibody
Gene Names
IKBIP; IKIP
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
IKBIP; Polyclonal Antibody; IKBIP Polyclonal Antibody; IKIP; anti-IKBIP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.8mg/mL (varies by lot)
Sequence Length
350
Applicable Applications for anti-IKBIP antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human IKBIP
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using IKBIP Polyclonal Antibody at dilution 1:40)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using IKBIP Polyclonal Antibody at dilution 1:40)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using IKBIP Polyclonal Antibody at dilution 1:40)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using IKBIP Polyclonal Antibody at dilution 1:40)
Related Product Information for anti-IKBIP antibody
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
Product Categories/Family for anti-IKBIP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
43,084 Da
NCBI Official Full Name
Inhibitor of nuclear factor kappa-B kinase-interacting protein
NCBI Official Synonym Full Names
IKBKB interacting protein
NCBI Official Symbol
IKBIP
NCBI Official Synonym Symbols
IKIP
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase-interacting protein; I kappa B kinase interacting protein; IKBKB-interacting protein; IKK interacting protein; IKK-interacting protein; i kappa-B kinase-interacting protein
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase-interacting protein
UniProt Gene Name
IKBIP
UniProt Synonym Gene Names
IKIP; I kappa-B kinase-interacting protein; IKBKB-interacting protein; IKK-interacting protein
UniProt Entry Name
IKIP_HUMAN
Uniprot Description
IKIP: Target of p53/TP53 with pro-apoptotic function. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 12q23.1
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: protein binding
Biological Process: response to X-ray
Research Articles on IKBIP
1. We conclude that IKIP is a novel p53 target gene with proapoptotic function.(IKIP1 protein, human)
Similar Products
Product Notes
The IKBIP ikbip (Catalog #AAA2527690) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKBIP Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IKBIP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the IKBIP ikbip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKBIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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