Rabbit anti-Human VWA2 Polyclonal Antibody | anti-VWA2 antibody

VWA2, NT (VWA2, AMACO, von Willebrand factor A domain-containing protein 2, A domain-containing protein similar to matrilin and collagen, Colon cancer secreted protein 2) (MaxLight 750)

Cat. Num. AAA6362948

• Gene Names: VWA2; AMACO; CCSP2; NET42; CCSP-2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: VWA2; Polyclonal Antibody; NT (VWA2; AMACO; von Willebrand factor A domain-containing protein 2; A domain-containing protein similar to matrilin and collagen; Colon cancer secreted protein 2) (MaxLight 750); Colon cancer secreted protein 2; anti-VWA2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human VWA2.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-VWA2 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 44-72 in the N-terminal region of human VWA2.
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in NCI-H460 cell line lysates using (35ug/lane)MBS6009405. This demonstrates MBS6009405 detected the VWA2 protein (arrow).)

Related Product Information for anti-VWA2 antibody

VWA2, also named as AMACO and CCSP2, is a novel candidate serological marker of colon neoplasia. VWA2 is found in the media of variesy of established cell lines of both fibroblast and epithelial origin.

Product Categories/Family for anti-VWA2 antibody

Antibodies; Cancer Markers

References

1. Gao, W., et al. Blood 112(5):1713-1719(2008). 2. Gebauer, J.M., et al. J. Biol. Chem. 283(26):17846-17854(2008). 3. Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006). 4. Xin, B., et al. Oncogene 24(4):724-731(2005). 5. Eller, E., et al. Ann. N. Y. Acad. Sci. 1037:145-149 (2004).

NCBI and Uniprot Product Information

• NCBI GI #: 38348304
• NCBI GeneID: 340706
• NCBI Accession #: NP_940898.1
• NCBI GenBank Nucleotide #: NM_198496.1
• UniProt Accession #: Q5GFL6; Q6ZS39; Q6ZWJ7; Q708C5; Q70UZ8; A1A5D4; B5MDJ8
• Molecular Weight: 45,345 Da
• NCBI Official Synonym Full Names: von Willebrand factor A domain containing 2
• NCBI Official Symbol: VWA2
• NCBI Official Synonym Symbols: AMACO; CCSP2; NET42; CCSP-2
• NCBI Protein Information: von Willebrand factor A domain-containing protein 2
• UniProt Protein Name: von Willebrand factor A domain-containing protein 2
• Protein Family: von Willebrand factor A domain-containing protein
• UniProt Gene Name: VWA2
• UniProt Synonym Gene Names: AMACO; AMACO; CCSP-2

NCBI Description

This gene encodes a member of the von Willebrand factor A-like domain protein superfamily. The encoded protein is localized to the extracellular matrix and may serve as a structural component in basement membranes or in anchoring structures on scaffolds of collagen VII or fibrillin. This gene has been linked to type 1A diabetes and is a candidate serological marker for colon cancer. [provided by RefSeq, Jan 2013]