Western Blot (WB)
(Lane 1: Rat Liver Tissue Lysate; Lane 2: Rat Pancreas Tissue Lysate; Lane 3: Rat Brain Tissue Lysate; Lane 4: Rat Kidney Tissue Lysate; Lane 5: SMMC Cell Lysate)
Rabbit IGFBP6 Polyclonal Antibody | anti-IGFBP6 antibody
IGFBP6 Antibody
Gene Names
IGFBP6; IBP6
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
IGFBP6; Polyclonal Antibody; IGFBP6 Antibody; Affinity Purified Rabbit Polyclonal IGFBP6 Antibody; Polyclonal IGFBP6 antibody; Anti-IGFBP6 antibody; IGFBP 6; IGFBP-6; IGFBP-6 antibody; IGFBP 6 antibody; Insulin-like growth factor-binding protein 6 antibody; anti-IGFBP6 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
240
Applicable Applications for anti-IGFBP6 antibody
Western Blot (WB)
Immunogen
IGFBP6 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human IGFBP6, different from the related rat sequence by two amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Lane 1: Rat Liver Tissue Lysate; Lane 2: Rat Pancreas Tissue Lysate; Lane 3: Rat Brain Tissue Lysate; Lane 4: Rat Kidney Tissue Lysate; Lane 5: SMMC Cell Lysate)
Western Blot (WB)
(Lane 1: Rat Liver Tissue Lysate; Lane 2: Rat Pancreas Tissue Lysate; Lane 3: Rat Brain Tissue Lysate; Lane 4: Rat Kidney Tissue Lysate; Lane 5: SMMC Cell Lysate)
Related Product Information for anti-IGFBP6 antibody
Insulin-like growth factor-binding protein 6 (IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22,847 Da. Kato et al. (1995) showed that the human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor.
Product Categories/Family for anti-IGFBP6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
insulin-like growth factor-binding protein 6
NCBI Official Synonym Full Names
insulin like growth factor binding protein 6
NCBI Official Symbol
IGFBP6
NCBI Official Synonym Symbols
IBP6
NCBI Protein Information
insulin-like growth factor-binding protein 6
UniProt Protein Name
Insulin-like growth factor-binding protein 6
Protein Family
UniProt Gene Name
IGFBP6
UniProt Synonym Gene Names
IBP6; IBP-6; IGF-binding protein 6; IGFBP-6
UniProt Entry Name
IBP6_HUMAN
Uniprot Description
IGFBP6: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Protein type: Cell cycle regulation; Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: Golgi apparatus; extracellular space; extracellular region
Molecular Function: insulin-like growth factor I binding; insulin-like growth factor II binding
Biological Process: negative regulation of cell proliferation; cellular protein metabolic process; regulation of insulin-like growth factor receptor signaling pathway; regulation of cell growth; signal transduction
Research Articles on IGFBP6
1. IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling
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Product Notes
The IGFBP6 igfbp6 (Catalog #AAA5312730) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IGFBP6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IGFBP6 igfbp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGFBP6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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