Western Blot (WB)
(IFT88 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).)
Rabbit anti-Human, mouse IFT88 Polyclonal Antibody | anti-IFT88 antibody
IFT88 Antibody (C-term)
Western Blot (WB)
(IFT88 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).)
Western Blot (WB)
(IFT88 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).)
Western Blot (WB)
(IFT88 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).)
Western Blot (WB)
(IFT88 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).)
Immunohistochemistry (IHC)
(IFT88 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IFT88 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(IFT88 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IFT88 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunofluorescence (IF)
(Confocal immunofluorescent analysis of IFT88 Antibody (C-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).)
Immunofluorescence (IF)
(Confocal immunofluorescent analysis of IFT88 Antibody (C-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).)
repeat (TPR) family. Mutations of a similar gene in mouse can cause
polycystic kidney disease. Two transcript variants encoding
distinct isoforms have been identified for this gene. [provided by
RefSeq].
Robert, A., et al. J. Cell. Sci. 120 (PT 4), 628-637 (2007) :
Khanna, H., et al. J. Biol. Chem. 280(39):33580-33587(2005)
Lehner, B., et al. Genomics 83(1):153-167(2004)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TTC10: Involved in primary cilium biogenesis. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 13q12.1
Cellular Component: centriole; apical part of cell; motile primary cilium; photoreceptor connecting cilium; acrosomal membrane; cilium
Molecular Function: kinesin binding
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; epidermis development; regulation of fat cell differentiation; spinal cord dorsal/ventral patterning; palate development; cardiac muscle cell differentiation; cytoplasmic microtubule organization and biogenesis; anterior/posterior pattern formation; spermatid nuclear elongation; protein localization; pancreas development; kidney development; regulation of odontogenesis of dentine-containing teeth; negative regulation of epithelial cell proliferation; Notch signaling pathway; smoothened signaling pathway; organelle organization and biogenesis; liver development; forebrain morphogenesis; telencephalon development; inner ear receptor stereocilium organization and biogenesis; eye development; sperm axoneme assembly; embryonic digit morphogenesis; determination of left/right symmetry; regulation of smoothened signaling pathway
Research Articles on IFT88
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Product Notes
The IFT88 ift88 (Catalog #AAA9206426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 791-820. The IFT88 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IFT88 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). WB~~1:1000. Researchers should empirically determine the suitability of the IFT88 ift88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFT88, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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