Testing Data
(Mouse testis tissue were subjected to SDS PAGE followed by western blot with IFT140 antibody at dilution of 1:300)
Rabbit IFT140 Polyclonal Antibody | anti-IFT140 antibody
IFT140 Antibody
IF: 1:20-200
Testing Data
(Mouse testis tissue were subjected to SDS PAGE followed by western blot with IFT140 antibody at dilution of 1:300)
Testing Data
(Mouse testis tissue were subjected to SDS PAGE followed by western blot with IFT140 antibody at dilution of 1:300)
NCBI and Uniprot Product Information
Observed MW: 140kDa
NCBI Description
This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012]
Uniprot Description
IFT140: Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance. Defects in IFT140 are the cause of Mainzer-Saldino syndrome (MZSDS). MZSDS is a rare autosomal recessive disease characterized by phalangeal cone- shaped epiphyses, chronic renal disease, nearly constant retinal dystrophy, and mild radiographic abnormality of the proximal femur. Occasional features include short stature, cerebellar ataxia, and hepatic fibrosis.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: centrosome; axoneme; photoreceptor connecting cilium
Biological Process: skeletal morphogenesis; retina development in camera-type eye; organelle organization and biogenesis; cilium biogenesis
Disease: Short-rib Thoracic Dysplasia 9 With Or Without Polydactyly
Research Articles on IFT140
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Product Notes
The IFT140 ift140 (Catalog #AAA2520225) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IFT140 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IFT140 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). WB: 1:200-1:2000 IF: 1:20-200. Researchers should empirically determine the suitability of the IFT140 ift140 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFT140, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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