Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46584(ICMT Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human, Mouse ICMT Polyclonal Antibody | anti-ICMT antibody
ICMT Antibody
Gene Names
ICMT; PCMT; PPMT; PCCMT; HSTE14; MST098; MSTP098
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ICMT; Polyclonal Antibody; ICMT Antibody; PCMT; PPMT; PCCMT; HSTE14; MST098; MSTP098; anti-ICMT antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total ICMT protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.6mg/ml (varies by lot)
Sequence Length
284
Applicable Applications for anti-ICMT antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 40-200
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human ICMT
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46584(ICMT Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46584(ICMT Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-ICMT antibody
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Product Categories/Family for anti-ICMT antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,938 Da
NCBI Official Full Name
protein-S-isoprenylcysteine O-methyltransferase
NCBI Official Synonym Full Names
isoprenylcysteine carboxyl methyltransferase
NCBI Official Symbol
ICMT
NCBI Official Synonym Symbols
PCMT; PPMT; PCCMT; HSTE14; MST098; MSTP098
NCBI Protein Information
protein-S-isoprenylcysteine O-methyltransferase
UniProt Protein Name
Protein-S-isoprenylcysteine O-methyltransferase
Protein Family
UniProt Gene Name
ICMT
UniProt Synonym Gene Names
PCCMT; PPMT; pcCMT
NCBI Description
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Research Articles on ICMT
Similar Products
Product Notes
The ICMT icmt (Catalog #AAA9429731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ICMT Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ICMT can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 40-200. Researchers should empirically determine the suitability of the ICMT icmt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ICMT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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