Western Blot (WB)
(Western blot analysis of IA-6 in rat thymus tissue lysate with IA-6 antibody at (A) 1 and (B) 2 μg/mL. )
Rabbit IA-6 Polyclonal Antibody | anti-INSM2 antibody
IA-6 Antibody
Gene Names
INSM2; IA6; IA-6; mlt1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
IA-6 Antibody is affinity chromatography purified via peptide column.
Synonyms
IA-6; Polyclonal Antibody; IA-6 Antibody; IA6; mlt1; Nbla106; Insulinoma-associated protein 2; Zinc finger protein IA-6; insulinoma-associated 2; anti-INSM2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
IA-6 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
566
Applicable Applications for anti-INSM2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
IA-6 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IA-6.
Buffer
IA-6 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
IA-6 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of IA-6 in rat thymus tissue lysate with IA-6 antibody at (A) 1 and (B) 2 μg/mL. )
Western Blot (WB)
(Western blot analysis of IA-6 in rat thymus tissue lysate with IA-6 antibody at (A) 1 and (B) 2 μg/mL. )
Related Product Information for anti-INSM2 antibody
IA-6 Antibody: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
59,491 Da
NCBI Official Full Name
Insulinoma-associated 2
NCBI Official Synonym Full Names
insulinoma-associated 2
NCBI Official Symbol
INSM2
NCBI Official Synonym Symbols
IA6; IA-6; mlt1
NCBI Protein Information
insulinoma-associated protein 2; zinc finger protein IA-6; insulinoma-associated protein IA-6
UniProt Protein Name
Insulinoma-associated protein 2
Protein Family
UniProt Gene Name
INSM2
UniProt Synonym Gene Names
IA6
UniProt Entry Name
INSM2_HUMAN
Uniprot Description
INSM2: May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
Protein type: C2H2-type zinc finger protein; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 14q13.2
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on INSM2
Similar Products
Product Notes
The INSM2 insm2 (Catalog #AAA150092) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IA-6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IA-6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the INSM2 insm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IA-6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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