Rabbit HtrA serine peptidase 4 Polyclonal Antibody | anti-HTRA4 antibody
Rabbit anti-human HtrA serine peptidase 4 polyclonal Antibody
WB: 1:200-1:2000 (Recommender dilutions)
Positive WB detected in : Human placenta tissue
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]
Uniprot Description
HTRA4: Serine protease (Probable). Belongs to the peptidase S1B family.
Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.-
Chromosomal Location of Human Ortholog: 8p11.22
Cellular Component: extracellular region
Molecular Function: insulin-like growth factor binding; serine-type endopeptidase activity; endopeptidase activity
Biological Process: regulation of cell growth; proteolysis; negative regulation of transforming growth factor beta receptor signaling pathway
Research Articles on HTRA4
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Product Notes
The HTRA4 htra4 (Catalog #AAA711440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human HtrA serine peptidase 4 polyclonal Antibody reacts with Human, Mouse,Rat; Other species are not tested. Please decide the specificity by homology. and may cross-react with other species as described in the data sheet. AAA Biotech's HtrA serine peptidase 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: Use at an assay dependent dilution. WB: 1:200-1:2000 (Recommender dilutions) Positive WB detected in : Human placenta tissue. Researchers should empirically determine the suitability of the HTRA4 htra4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HtrA serine peptidase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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