Rabbit anti-Human HTR3C Polyclonal Antibody | anti-HTR3C antibody

HTR3C Antibody

Cat. Num. AAA9603054

• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: HTR3C; Polyclonal Antibody; HTR3C Antibody; 5 HT3 C; 5 HT3C; 5 hydroxytryptamine (serotonin) receptor 3; family member C; 5 hydroxytryptamine (serotonin) receptor 3C ionotropic; 5 hydroxytryptamine receptor 3 subunit C; 5 hydroxytryptamine receptor 3C; Serotonin receptor 3C; anti-HTR3C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: HTR3C antibody detects endogenous levels of total HTR3C
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 447

• Applicable Applications for anti-HTR3C antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000
• Immunogen: A synthesized peptide derived from human HTR3C
• Subcellular Location: Cell Membrane; Multipass Membrane Protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
• Tissue Specificity: Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as well as fetal colon and kidney.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of HTR3C using HepG2 whole cell lysates)

Related Product Information for anti-HTR3C antibody

Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subunit Structure: Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3C sub-subfamily.

NCBI and Uniprot Product Information

• NCBI GI #: 47519867
• NCBI GeneID: 170572
• NCBI Accession #: NP_570126.2
• NCBI GenBank Nucleotide #: NM_130770.2
• UniProt Accession #: Q8WXA8; A2RRR5
• Molecular Weight: Observed: 50 kDa; Predicted: 51 kDa
• NCBI Official Full Name: 5-hydroxytryptamine receptor 3C
• NCBI Official Synonym Full Names: 5-hydroxytryptamine receptor 3C
• NCBI Official Symbol: HTR3C
• NCBI Protein Information: 5-hydroxytryptamine receptor 3C
• UniProt Protein Name: 5-hydroxytryptamine receptor 3C
• Protein Family: 5-hydroxytryptamine receptor
• UniProt Gene Name: HTR3C
• UniProt Synonym Gene Names: 5-HT3-C; 5-HT3C

NCBI Description

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008]

Uniprot Description

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.