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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/30.)

Rabbit anti-Human HTR3B Polyclonal Antibody | anti-HTR3B antibody

HTR3B Antibody

Gene Names
HTR3B; 5-HT3B
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
HTR3B; Polyclonal Antibody; HTR3B Antibody; 5-HT3B; anti-HTR3B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total HTR3B protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.6 mg/ml (varies by lot)
Sequence Length
441
Applicable Applications for anti-HTR3B antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Target Name
HTR3B
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)
Related Product Information for anti-HTR3B antibody
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.
Product Categories/Family for anti-HTR3B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,285 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 3B
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
NCBI Official Symbol
HTR3B
NCBI Official Synonym Symbols
5-HT3B
NCBI Protein Information
5-hydroxytryptamine receptor 3B
UniProt Protein Name
5-hydroxytryptamine receptor 3B
UniProt Gene Name
HTR3B
UniProt Synonym Gene Names
5-HT3-B; 5-HT3B
UniProt Entry Name
5HT3B_HUMAN

NCBI Description

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]

Uniprot Description

5-HT(3B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, cation; Transporter, ion channel; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 11q23.1

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane

Molecular Function: serotonin-activated cation-selective channel activity; serotonin receptor activity; ion channel activity

Biological Process: synaptic transmission; transport; transmembrane transport; serotonin receptor signaling pathway

Research Articles on HTR3B

Similar Products

Product Notes

The HTR3B htr3b (Catalog #AAA9410281) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HTR3B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HTR3B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the HTR3B htr3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTR3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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