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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7125771(HSD17B14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit anti-Human HSD17B14 Polyclonal Antibody | anti-HSD17B14 antibody

HSD17B14 Antibody

Gene Names
HSD17B14; DHRS10; SDR47C1; retSDR3
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
HSD17B14; Polyclonal Antibody; HSD17B14 Antibody; hydroxysteroid (17-beta) dehydrogenase 14; anti-HSD17B14 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-HSD17B14 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
IHC: 1:50-1:200
Immunogen
Fusion protein of human HSD17B14
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7125771(HSD17B14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7125771(HSD17B14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7125771(HSD17B14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7125771(HSD17B14 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))
Product Categories/Family for anti-HSD17B14 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,317 Da
NCBI Official Full Name
17-beta-hydroxysteroid dehydrogenase 14
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 14
NCBI Official Symbol
HSD17B14
NCBI Official Synonym Symbols
DHRS10; SDR47C1; retSDR3
NCBI Protein Information
17-beta-hydroxysteroid dehydrogenase 14; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; dehydrogenase/reductase (SDR family) member 10; dehydrogenase/reductase SDR family member 10; retinal short-chain dehydrogenase/reductase 3; retinal shor
UniProt Protein Name
17-beta-hydroxysteroid dehydrogenase 14
UniProt Gene Name
HSD17B14
UniProt Synonym Gene Names
DHRS10; SDR3; 17-beta-HSD 14
UniProt Entry Name
DHB14_HUMAN

NCBI Description

17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]

Uniprot Description

HSD17B14: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: Oxidoreductase; EC 1.1.1.-

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cytosol

Molecular Function: estradiol 17-beta-dehydrogenase activity; protein binding; testosterone 17-beta-dehydrogenase (NADP+) activity

Biological Process: steroid catabolic process

Research Articles on HSD17B14

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Product Notes

The HSD17B14 hsd17b14 (Catalog #AAA7125771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HSD17B14 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSD17B14 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the HSD17B14 hsd17b14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSD17B14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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