Western Blot (WB)
(All lanes : Anti-HPN Antibody (Center) at 1:2000 dilutionLane 1: Hela whole cell lysateLane 2: MCF-7 whole cell lysateLane 3: SW620 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human HPN Polyclonal Antibody | anti-HPN antibody
HPN Antibody (Center)
Western Blot (WB)
(All lanes : Anti-HPN Antibody (Center) at 1:2000 dilutionLane 1: Hela whole cell lysateLane 2: MCF-7 whole cell lysateLane 3: SW620 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-HPN Antibody (Center) at 1:2000 dilutionLane 1: Hela whole cell lysateLane 2: MCF-7 whole cell lysateLane 3: SW620 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Background: Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Uniprot Description
HPN: Plays an essential role in cell growth and maintenance of cell morphology. Belongs to the peptidase S1 family.
Protein type: Membrane protein, integral; EC 3.4.21.106; Protease
Chromosomal Location of Human Ortholog: 19q13.12
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; cell surface; cell soma; integral to plasma membrane; plasma membrane; integral to membrane; intercellular junction
Molecular Function: peptidase activity; calcium-activated potassium channel activity; protein binding; serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: regulation of cell shape; cholesterol homeostasis; detection of mechanical stimulus involved in sensory perception of sound; proteolysis; positive regulation of cell growth; negative regulation of epithelial cell proliferation; negative regulation of apoptosis
Research Articles on HPN
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Product Notes
The HPN hpn (Catalog #AAA9232123) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HPN Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HPN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:2000. Researchers should empirically determine the suitability of the HPN hpn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HPN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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