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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47704(HPN Antibody) at dilution 1/50.(Original magnification: 200))

Rabbit HPN Polyclonal Antibody | anti-HPN antibody

HPN Antibody

Gene Names
HPN; TMPRSS1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
HPN; Polyclonal Antibody; HPN Antibody; TMPRSS1; anti-HPN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total HPN protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.8 mg/mL (varies by lot)
Sequence Length
417
Applicable Applications for anti-HPN antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-300
Immunogen
Fusion protein of human HPN
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47704(HPN Antibody) at dilution 1/50.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47704(HPN Antibody) at dilution 1/50.(Original magnification: 200))
Related Product Information for anti-HPN antibody
This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-HPN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,011 Da
NCBI Official Full Name
serine protease hepsin
NCBI Official Synonym Full Names
hepsin
NCBI Official Symbol
HPN
NCBI Official Synonym Symbols
TMPRSS1
NCBI Protein Information
serine protease hepsin
UniProt Protein Name
Serine protease hepsin
UniProt Gene Name
HPN
UniProt Synonym Gene Names
TMPRSS1

NCBI Description

This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Description

Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890).

Research Articles on HPN

Similar Products

Product Notes

The HPN hpn (Catalog #AAA9430686) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HPN Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HPN can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the HPN hpn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HPN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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