Goat HOXD12 Polyclonal Antibody | anti-HOXD12 antibody
Goat anti-HOXD12 Antibody
Western Blot: Approx 37kDa band observed in Human Heart lysates (calculated MW of 29. 0kDa according to NP_067016.3). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 2-3ug/ml.
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
HOXD12: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: nucleus; transcription factor complex
Molecular Function: protein binding; sequence-specific DNA binding
Biological Process: embryonic digit morphogenesis; pattern specification process; regulation of transcription, DNA-dependent; skeletal development; transcription, DNA-dependent
Research Articles on HOXD12
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Product Notes
The HOXD12 hoxd12 (Catalog #AAA423042) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-HOXD12 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's HOXD12 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx 37kDa band observed in Human Heart lysates (calculated MW of 29. 0kDa according to NP_067016.3). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 2-3ug/ml. Researchers should empirically determine the suitability of the HOXD12 hoxd12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PTAKDGPEEQ AK. It is sometimes possible for the material contained within the vial of "HOXD12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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