Rabbit HOXC11 Polyclonal Antibody | anti-HOXC11 antibody

HOXC11 antibody - middle region

Cat. Num. AAA3201069

• Gene Names: HOXC11; HOX3H
• Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Protein A purified
• Synonyms: HOXC11; Polyclonal Antibody; HOXC11 antibody - middle region; anti-HOXC11 antibody

• Host: Rabbit
• Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Clonality: Polyclonal
• Purity/Purification: Protein A purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: DRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEA
• Sequence Length: 304

• Applicable Applications for anti-HOXC11 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC11
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Immunohistochemistry (IHC)

(Sample Type :Mouse lumbar spinal cord sectionsPrimary Antibody Dilution :1:1000Secondary Antibody :Anti-rabbit-Cy3Secondary Antibody Dilution :1:800Color/Signal Descriptions :Red: HOXC11Gene Name :HOXC11Submitted by :Anonymous)

Western Blot (WB)

(Host: RabbitTarget Name: HOXC11Sample Tissue: Human RPMI 8226 Whole CellAntibody Dilution: 1ug/ml)

Western Blot (WB)

(WB Suggested Anti-HOXC11 Antibody Titration: 1.25ug/mlPositive Control: Transfected 293T)

Related Product Information for anti-HOXC11 antibody

This is a rabbit polyclonal antibody against HOXC11. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

Product Categories/Family for anti-HOXC11 antibody

Polyclonal; Transcription Factor; Transcription Regulation; Developmental Biology; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 7657166
• NCBI GeneID: 3227
• NCBI Accession #: NP_055027
• NCBI GenBank Nucleotide #: NM_014212
• UniProt Accession #: O43248
• Molecular Weight: 34kDa
• NCBI Official Full Name: homeobox protein Hox-C11
• NCBI Official Synonym Full Names: homeobox C11
• NCBI Official Symbol: HOXC11
• NCBI Official Synonym Symbols: HOX3H
• NCBI Protein Information: homeobox protein Hox-C11
• UniProt Protein Name: Homeobox protein Hox-C11
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXC11
• UniProt Synonym Gene Names: HOX3H
• UniProt Entry Name: HXC11_HUMAN

NCBI Description

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXC11: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; induction of an organ; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; metanephros development; proximal/distal pattern formation; endoderm development