Rabbit anti-Human HOXB9 Polyclonal Antibody | anti-HOXB9 antibody

HOXB9, ID (HOXB9, HOX2E, Homeobox protein Hox-B9, Homeobox protein Hox-2.5, Homeobox protein Hox-2E) (FITC)

Cat. Num. AAA6307938

• Gene Names: HOXB9; HOX2; HOX2E; HOX-2.5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: HOXB9; Polyclonal Antibody; ID (HOXB9; HOX2E; Homeobox protein Hox-B9; Homeobox protein Hox-2.5; Homeobox protein Hox-2E) (FITC); Homeobox protein Hox-2E; anti-HOXB9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-HOXB9 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: HOXB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human HOXB9.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HOXB9 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HOXB9 antibody detected the HOXB9 protein (arrow).)

Related Product Information for anti-HOXB9 antibody

HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.

Product Categories/Family for anti-HOXB9 antibody

Antibodies; Transcription Factors; Zinc; Ring; Homeobox

References

Hayashida, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(3):1100-1105(2010). Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009). Rouault, K., et al. Osteoarthr. Cartil. 17(8):1099-1105(2009). Nguyen, D.X., et al. Cell 138(1):51-62(2009). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 15029508
• NCBI GeneID: 3219
• NCBI Accession #: NP_076922.1
• NCBI GenBank Nucleotide #: NM_024017.4
• UniProt Accession #: P17482; Q9H1I1; B2RDB7
• Molecular Weight: 28,059 Da
• NCBI Official Full Name: homeobox protein Hox-B9
• NCBI Official Synonym Full Names: homeobox B9
• NCBI Official Symbol: HOXB9
• NCBI Official Synonym Symbols: HOX2; HOX2E; HOX-2.5
• NCBI Protein Information: homeobox protein Hox-B9; homeo box 2E; homeo box B9; homeobox protein Hox-2E; homeobox protein Hox-2.5
• UniProt Protein Name: Homeobox protein Hox-B9
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXB9
• UniProt Synonym Gene Names: HOX2E
• UniProt Entry Name: HXB9_HUMAN

NCBI Description

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXB9: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: nucleoplasm; mitochondrion

Molecular Function: protein binding; sequence-specific DNA binding

Biological Process: anterior/posterior pattern formation; mammary gland development; transcription, DNA-dependent; embryonic skeletal development; positive regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin