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Rabbit anti-Human Holliday junction recognition protein Polyclonal Antibody | anti-HJURP antibody

Rabbit anti-human Holliday junction recognition protein polyclonal Antibody, HRP conjugated

Gene Names
HJURP; FAKTS; URLC9; hFLEG1
Reactivity
Human
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Holliday junction recognition protein; Polyclonal Antibody; Rabbit anti-human Holliday junction recognition protein polyclonal Antibody; HRP conjugated; 14-3-3-associated AKT substrate; Fetal liver-expressing gene 1 protein; Up-regulated in lung cancer 9; HJURP; FAKTS; FLEG1; URLC9; anti-HJURP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
694
Applicable Applications for anti-HJURP antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human Holliday junction recognition protein(1-748aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168091 / sc-134696
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-HJURP antibody
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
74,372 Da
NCBI Official Full Name
Holliday junction recognition protein isoform b
NCBI Official Synonym Full Names
Holliday junction recognition protein
NCBI Official Symbol
HJURP
NCBI Official Synonym Symbols
FAKTS; URLC9; hFLEG1
NCBI Protein Information
Holliday junction recognition protein
UniProt Protein Name
Holliday junction recognition protein
UniProt Gene Name
HJURP
UniProt Entry Name
HJURP_HUMAN

Uniprot Description

FLEG1: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; Histone-binding

Chromosomal Location of Human Ortholog: 2q37.1

Cellular Component: chromosome, pericentric region; cytoplasm; nucleolus; nucleoplasm; nucleus

Molecular Function: DNA binding; histone binding; identical protein binding; protein binding

Biological Process: cell cycle; chromosome segregation; DNA replication-independent nucleosome assembly at centromere; nucleosome assembly; regulation of DNA binding; regulation of protein complex assembly

Research Articles on HJURP

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Product Notes

The HJURP hjurp (Catalog #AAA1495089) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Holliday junction recognition protein polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Holliday junction recognition protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the HJURP hjurp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Holliday junction recognition protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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