Rabbit anti-Human, Mouse HMX3 Polyclonal Antibody | anti-HMX3 antibody

Rabbit Polyclonal to Mouse HMX3

Cat. Num. AAA244335

• Gene Names: HMX3; NKX5.1; Nkx5-1; NKX-5.1
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: HMX3; Polyclonal Antibody; Rabbit Polyclonal to Mouse HMX3; Anti-HMX3 Antibody (C-Terminus) IHC-plus; Homeobox protein HMX3; Homeobox protein Nkx-5.1; H6 family homeobox 3; Homeobox (H6 family) 3; NKX5.1; NKX-5.1; Nkx5-1; Homeo box (H6 family) 3; Mouse HMX3; anti-HMX3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.09% sodium azide
• Sequence Length: 357

• Applicable Applications for anti-HMX3 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB (1:1000)
• Target Species: Mouse
• Immunogen Description: KLH conjugated synthetic peptide selected from the C-terminal region of mouse Hmx3.
• Immunogen Type: Synthetic peptide
• Immunogen: HMX3 antibody was raised against kLH conjugated synthetic peptide selected from the C-terminal region of mouse Hmx3.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-HMX3 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Western Blot (WB)

(Western blot of anti-Mouse Hmx3 Antibody (C-term) in mouse stomach tissue lysates (35 ug/lane). Hmx3(arrow) was detected using the purified Pab)

NCBI and Uniprot Product Information

• NCBI GI #: 157743259
• NCBI GeneID: 340784
• NCBI Accession #: NP_001099044.1
• NCBI GenBank Nucleotide #: NM_001105574.1
• UniProt Accession #: A6NHT5; A8MU06
• Molecular Weight: 37,825 Da
• NCBI Official Full Name: homeobox protein HMX3
• NCBI Official Synonym Full Names: H6 family homeobox 3
• NCBI Official Symbol: HMX3
• NCBI Official Synonym Symbols: NKX5.1; Nkx5-1; NKX-5.1
• NCBI Protein Information: homeobox protein HMX3; homeobox (H6 family) 3; homeo box (H6 family) 3; homeobox protein Nkx-5.1; homeobox protein H6 family member 3
• UniProt Protein Name: Homeobox protein HMX3
• Protein Family: Homeobox protein
• UniProt Gene Name: HMX3
• UniProt Synonym Gene Names: NKX-5.1; NKX5-1
• UniProt Entry Name: HMX3_HUMAN

Uniprot Description

HMX3: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS. Belongs to the HMX homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: inner ear morphogenesis; maternal process involved in pregnancy; regulation of transcription, DNA-dependent; transcription, DNA-dependent; brain development; neuromuscular process controlling balance; cell differentiation; embryo implantation