Western Blot (WB)
(Western blot analysis of HMGCS1 antibody (C-term) in K562 cell line lysates (35ug/lane). NKRF (arrow) was detected using the purified Pab.)
Rabbit HMGCS1 Polyclonal Antibody | anti-HMGCS1 antibody
HMGCS1 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of HMGCS1 antibody (C-term) in K562 cell line lysates (35ug/lane). NKRF (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of HMGCS1 antibody (C-term) in K562 cell line lysates (35ug/lane). NKRF (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HMGCS1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HMGCS1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of hela cells using HMGCS1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of hela cells using HMGCS1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.
Protein type: Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.3.10
Chromosomal Location of Human Ortholog: 5p14-p13
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus; cytosol
Molecular Function: protein homodimerization activity; organic acid binding; hydroxymethylglutaryl-CoA synthase activity; drug binding; isomerase activity
Biological Process: response to purine; response to drug; isoprenoid biosynthetic process; male gonad development; cellular lipid metabolic process; liver development; cholesterol biosynthetic process; response to low light intensity; response to vitamin E; response to tellurium ion; response to lipoprotein stimulus; lipid metabolic process; brain development
Research Articles on HMGCS1
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Product Notes
The HMGCS1 hmgcs1 (Catalog #AAA9204613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 442-470. The HMGCS1 Antibody (C-term) reacts with Human (Predicted Reactivity: Chicken, Hamster, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's HMGCS1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the HMGCS1 hmgcs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMGCS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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