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Rabbit anti-Human HMGCLL1 Polyclonal Antibody | anti-HMGCLL1 antibody

HMGCLL1 Antibody

Gene Names
HMGCLL1; er-cHL; bA418P12.1
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
HMGCLL1; Polyclonal Antibody; HMGCLL1 Antibody; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; cytoplasmic (EC:4.1.3.4); 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1; Endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase; er-cHL; anti-HMGCLL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
340
Applicable Applications for anti-HMGCLL1 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-HMGCLL1 antibody
Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,701 Da
NCBI Official Full Name
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform b
NCBI Official Synonym Full Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
NCBI Official Symbol
HMGCLL1
NCBI Official Synonym Symbols
er-cHL; bA418P12.1
NCBI Protein Information
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic
UniProt Protein Name
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic
UniProt Gene Name
HMGCLL1
UniProt Synonym Gene Names
er-cHL
UniProt Entry Name
HMGC2_HUMAN

Uniprot Description

HMGCLL1: Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues. Belongs to the HMG-CoA lyase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Lyase; EC 4.1.3.4

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; perinuclear region of cytoplasm

Molecular Function: hydroxymethylglutaryl-CoA lyase activity; metal ion binding

Biological Process: cellular lipid metabolic process; ketone body biosynthetic process; ketone body metabolic process

Research Articles on HMGCLL1

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Product Notes

The HMGCLL1 hmgcll1 (Catalog #AAA1494218) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMGCLL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HMGCLL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the HMGCLL1 hmgcll1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMGCLL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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