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Western Blot (WB) (Western Blot (WB) analysis of HKR1 (W154) pAb at 1:1000 dilutionLane1:HEK293T whole cell lysate (20ug) Lane2:A549 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug))

Rabbit anti-Human HKR1 Polyclonal Antibody | anti-HKR1 antibody

HKR1 (W154) Polyclonal Antibody

Gene Names
ZNF875; HKR1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
HKR1; Polyclonal Antibody; HKR1 (W154) Polyclonal Antibody; Krueppel-related zinc finger protein 1; Protein HKR1; Zinc finger protein 875; ZNF875; anti-HKR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
HKR1 (W154) polyclonal antibody detects endogenous levels of HKR1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
659
Applicable Applications for anti-HKR1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 111-160 of Human HKR1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of HKR1 (W154) pAb at 1:1000 dilutionLane1:HEK293T whole cell lysate (20ug) Lane2:A549 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug))

Western Blot (WB) (Western Blot (WB) analysis of HKR1 (W154) pAb at 1:1000 dilutionLane1:HEK293T whole cell lysate (20ug) Lane2:A549 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug))

Immunohistochemistry (IHC)

(Immunohistochemistry (IHC) analyzes of HKR1 (W154) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.)

Immunohistochemistry (IHC) (Immunohistochemistry (IHC) analyzes of HKR1 (W154) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.)
Related Product Information for anti-HKR1 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 73kDa
NCBI Official Full Name
zinc finger protein 875 isoform a
NCBI Official Synonym Full Names
zinc finger protein 875
NCBI Official Symbol
ZNF875
NCBI Official Synonym Symbols
HKR1
NCBI Protein Information
zinc finger protein 875
UniProt Protein Name
Krueppel-related zinc finger protein 1
Protein Family
UniProt Gene Name
HKR1
UniProt Synonym Gene Names
ZNF875
UniProt Entry Name
HKR1_HUMAN

Uniprot Description

HKR1: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development

Research Articles on HKR1

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Product Notes

The HKR1 hkr1 (Catalog #AAA3001880) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HKR1 (W154) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HKR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the HKR1 hkr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HKR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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