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Testing Data

Rabbit anti-Human HJURP Polyclonal Antibody | anti-HJURP antibody

HJURP Antibody

Gene Names
HJURP; FAKTS; URLC9; hFLEG1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
HJURP; Polyclonal Antibody; HJURP Antibody; DKFZp762E1312; FAKTS; URLC9; hFLEG1; anti-HJURP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
663
Applicable Applications for anti-HJURP antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:200-1:2000
Immunogen
Fusion protein of HJURP
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168091 / sc-134696
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,372 Da
NCBI Official Full Name
Holliday junction recognition protein isoform c
NCBI Official Synonym Full Names
Holliday junction recognition protein
NCBI Official Symbol
HJURP
NCBI Official Synonym Symbols
FAKTS; URLC9; hFLEG1
NCBI Protein Information
Holliday junction recognition protein; 14-3-3-associated AKT substrate; fetal liver expressing gene 1; fetal liver-expressing gene 1 protein; up-regulated in lung cancer 9
UniProt Protein Name
Holliday junction recognition protein
UniProt Gene Name
HJURP
UniProt Entry Name
HJURP_HUMAN

Uniprot Description

FLEG1: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Histone-binding; Nucleolus

Chromosomal Location of Human Ortholog: 2q37.1

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus; chromosome, pericentric region

Molecular Function: identical protein binding; protein binding; DNA binding; histone binding

Biological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; regulation of DNA binding; regulation of protein complex assembly; cell cycle; chromosome segregation

Research Articles on HJURP

Similar Products

Product Notes

The HJURP hjurp (Catalog #AAA2518891) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HJURP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HJURP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:2000. Researchers should empirically determine the suitability of the HJURP hjurp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HJURP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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