Rabbit Histone H4, Dimethyl Symmetric Polyclonal Antibody

Histone H4, Dimethyl Symmetric (Arg3) (HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4

Cat. Num. AAA6010099

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunoprecipitation, Immunocytochemistry, Gel Super Shift Assay
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Histone H4; Dimethyl Symmetric; Polyclonal Antibody; Dimethyl Symmetric (Arg3) (HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4; Anti -Histone H4; anti-Histone H4; Dimethyl Symmetric antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes human Histone H4. Species Crossreactivity
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide, 30% glycerol.

• Applicable Applications for anti-Histone H4, Dimethyl Symmetric antibody: Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Gel Shift Assay (GS/EMSA)
• Application Notes: Suitable for use in Western Blot, Dot Blot, Chromatin Immunoprecipitation and Immunocytochemistry.
• Immunogen: Synthetic linear peptide corresponding to human Histone H4 (KLH).
• Positive Control: Includes normal rabbit IgG and primers specific for human B-globin
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-Histone H4, Dimethyl Symmetric antibody

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Histones are modified post-translationally by the actions of enzymes in both the nucleus and cytoplasm. These modifications, which include acetylation, phosphorylation, methylation, and ubiquitin-ation, occur predominantly on the N-terminal and C-terminal tails that extend beyond the nucleosome core particle. Arginine modifications of histones proteins are mediated by two classes of protein arginine methyltransferases (PRMTs), class I and II. Class I PRMTs place two methyl groups on the one nitrogen atom of the arginine guanidino group, resulting in an asymmetric modification. In contrast class II PRMTs place two methyl groups on two nitrogen atoms of the guanidino group producing a symmetric dimethylation. Although there are exceptions, asymmetric modifications are typically associated with transcription activation while symmetric modifications are most commonly associated with transcriptional repression.

Product Categories/Family for anti-Histone H4, Dimethyl Symmetric antibody

Antibodies; Abs to Histones