Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse High Mobility Group AT Hook Protein 2 (HMGA2) Polyclonal Antibody | anti-HMGA2 antibody
Polyclonal Antibody to High Mobility Group AT Hook Protein 2 (HMGA2)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-MSARGEGAGQ PSTSAQGQPA APVPQKRGRG RPRKQQQEPT CEPSPKRPRG RPKGSKNKSP SKAAQKKAET IGEKRPRGRP RKWPQQVVQK KPAQETEETS SQESAEED
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
HMGA2: Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Interacts with E4F1. Interacts with NEK2. Belongs to the HMGA family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Oncoprotein
Chromosomal Location of Human Ortholog: 10 D2|10 67.94 cM
Cellular Component: chromatin; nuclear chromosome; nucleus
Molecular Function: AT DNA binding; DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; enzyme binding; protein binding
Biological Process: adrenal gland development; base-excision repair; cell cycle; cell division; cell proliferation; cell proliferation in forebrain; chromosome condensation; male gonad development; meiotic cell cycle; negative regulation of astrocyte differentiation; negative regulation of JAK-STAT cascade; negative regulation of steroid hormone receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; negative regulation of Wnt signaling pathway; pituitary gland development; positive regulation of cell proliferation; positive regulation of multicellular organism growth; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of growth; regulation of growth hormone secretion; regulation of transcription, DNA-templated; signal transduction; somatic stem cell maintenance; spermatogenesis; transcription, DNA-dependent
Research Articles on HMGA2
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Product Notes
The HMGA2 hmga2 (Catalog #AAA2005189) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to High Mobility Group AT Hook Protein 2 (HMGA2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's High Mobility Group AT Hook Protein 2 (HMGA2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the HMGA2 hmga2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-MSA RGEGAGQ PSTSAQGQPA APVPQKRGRG RPRKQQQEPT CEPSPKRPRG RPKGSKNKSP SKAAQKKAET IGEKRPRGRP RKWPQQVVQK KPAQETEETS SQESAEED. It is sometimes possible for the material contained within the vial of "High Mobility Group AT Hook Protein 2 (HMGA2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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