Western Blot (WB)
(Marker, Lane 1: MCF-7 Cell Lysate, Lane 2: Hela Cell Lysate, Lane 3: Jurkat Cell Lysate, Lane 4: SMMC Cell Lysate, Lane 5: HT1080 Cell Lysate)
Rabbit HIF1 Alpha Polyclonal Antibody | anti-HIF1-alpha antibody
HIF1 Alpha Antibody
Gene Names
HIF1A; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
HIF1 Alpha; Polyclonal Antibody; HIF1 Alpha Antibody; Affinity Purified Mouse Polyclonal HIF1 alpha Antibody; Polyclonal HIF1 alpha antibody; Anti-HIF1 alpha antibody; Member of the PAS Superfamily 1 antibody; Hypoxia inducible factor 1 alpha isoform I.3 antibody; MOP1 antibody; PAS domain-containing protein 8 antibody; ARNT-interacting protein antibody; Basic helix loop helix PAS protein MOP1 antibody; MOP 1 antibody; Class E basic helix-loop-helix protein 78 antibody; HIF 1A antibody; Hypoxia inducible factor 1 alpha subunit antibody; Member of PAS protein 1 antibody; PASD 8 antibody PASD8 antibody; Hypoxia-inducible factor 1-alpha antibody; Member of PAS superfamily 1 antibody; Hypoxia inducible factor 1 alpha antibody; bHLHe78 antibody; Basic-helix-loop-helix-PAS protein MOP1 antibody; Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor antibody; ARNT interacting protein antibody; anti-HIF1-alpha antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
826
Applicable Applications for anti-HIF1-alpha antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
HIF1 alpha antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human HIF1 alpha, different from the related rat and Rabbit sequences by two amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Marker, Lane 1: MCF-7 Cell Lysate, Lane 2: Hela Cell Lysate, Lane 3: Jurkat Cell Lysate, Lane 4: SMMC Cell Lysate, Lane 5: HT1080 Cell Lysate)
Western Blot (WB)
(Marker, Lane 1: MCF-7 Cell Lysate, Lane 2: Hela Cell Lysate, Lane 3: Jurkat Cell Lysate, Lane 4: SMMC Cell Lysate, Lane 5: HT1080 Cell Lysate)
Related Product Information for anti-HIF1-alpha antibody
Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), also known as HIF1A, is a protein that in humans is encoded by the HIF1A gene. Two alternative transcripts encoding different isoforms have been identified. HIF1 is a homodimeric basic helix-loop-helix structure composed of Hif1a, the alpha subunit (this protein), and the aryl hydrocarbon receptor nuclear translocator (Arnt), the beta subunit. The protein encoded by HIF1 is a bHLH - PAS transcription factor found in mammalian cells growing at low oxygen concentrations. It plays an essential role in cellular and systemic responses to hypoxia. This is one of the class of hypoxia inducible factors, a family that includes Hif1a, Hif2a, and Hif3a.
Product Categories/Family for anti-HIF1-alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
NCBI Official Synonym Full Names
hypoxia inducible factor 1 subunit alpha
NCBI Official Symbol
HIF1A
NCBI Official Synonym Symbols
HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
NCBI Protein Information
hypoxia-inducible factor 1-alpha
NCBI Description
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Research Articles on HIF1-alpha
Similar Products
Product Notes
The HIF1-alpha (Catalog #AAA5312554) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HIF1 Alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the HIF1-alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIF1 Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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