Rabbit anti-Mouse Hexokinase, Pan Polyclonal Antibody | anti-HKL3 antibody
Anti-Hexokinase, Pan (HXK1, HXK2, HXK3)
Gene Names
HKL3; hexokinase-like 3; HKL3; T28I19.120; T28I19_120
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Hexokinase; Pan; Polyclonal Antibody; Anti-Hexokinase; Pan (HXK1; HXK2; HXK3); HXK1; HXK3; anti-HKL3 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse HKX1, 2 and 3.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-HKL3 antibody
ELISA; Western Blot; Immunohistochemistry
Application Notes
Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Recommended Dilutions: ELISA: 0.5-1ug/ml
Western Blot: 1-10ug/ml
Immunohistochemistry: 5-20ug/ml
Recommended Dilutions: ELISA: 0.5-1ug/ml
Western Blot: 1-10ug/ml
Immunohistochemistry: 5-20ug/ml
Immunogen
Synthetic peptide corresponding to 15aa of mouse HXK1/2, C-terminal (KLH).
Source Information
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-HKL3 antibody
Hexokinase catalyzes the first step of several metabolic pathways by converting D-hexose to D-hexose-6-P. Hexokinase is an allosteric enzyme inhibited by its products glucose-6-phosphate. At least 4 related hexokinase isoforms (HXKI-III; HXK-IV also known as Glucokinase) have been cloned and characterized. Hexokinases (~100kD for HXK1-III; HXKIV lacks the N-terminal domains and is ~50kD) are outer mitochondrial membrane proteins. The N- terminus, containing the mitochondrial target sequence, and the C- terminal has high sequence homology among various isoforms. The catalytic activity is associated with the C-terminus and other regulatory functions are controlled by the N-terminus. HXK1 is located on chromosome 10. It exists either as a cytosolic protein or as a protein associated with the outer mitochondrial membrane via an interaction with porin, a voltage-dependent anion channel. HXK1/HK1 is alternatively spliced into 3 isoforms: HK1-SA (975aa) and HK1-SB and HK1-SC are alternatively spliced at Met-1 and Met- 53. Isoform HK1-SA (1-974aa), isoform HK1-SB and isoform HK1- SC (53-974aa) are found only in spermatogenic cells. Isoform HK1- SC is detected in round spermatids, condensing spermatids and mature sperm where it is found in the head membranes, mitochondria of the midpiece and the fibrous sheath of the flagellum. Defects in HK1 gene causes hemolytic anemia.
Product Categories/Family for anti-HKL3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
hexokinase
NCBI Official Symbol
HKL3
NCBI Official Synonym Symbols
hexokinase-like 3; HKL3; T28I19.120; T28I19_120
NCBI Protein Information
hexokinase
Similar Products
Product Notes
The HKL3 (Catalog #AAA629386) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hexokinase, Pan (HXK1, HXK2, HXK3) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Hexokinase, Pan can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot; Immunohistochemistry. Suitable for use in ELISA, Immunohistochemistry and Western Blot. Recommended Dilutions: ELISA: 0.5-1ug/ml Western Blot: 1-10ug/ml Immunohistochemistry: 5-20ug/ml. Researchers should empirically determine the suitability of the HKL3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hexokinase, Pan, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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