Western Blot (WB)
(Western Blot analysis of various samples using HES1 Polyclonal Antibody at dilution of 1:600.)
Rabbit anti-Mouse, Rat HES1 Polyclonal Antibody | anti-HES1 antibody
HES1 Polyclonal Antibody
Gene Names
Hes1; Hry; bHLHb39
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Affinity Purification
Synonyms
HES1; Polyclonal Antibody; HES1 Polyclonal Antibody; bHLHb39; C-HAIRY1; c-hairy1A; Class B basic helix-loop-helix protein 39; FLJ20408; Hairy and enhancer of split 1 (Drosophila); Hairy and enhancer of split 1; Hairy homolog (Drosophila); Hairy homolog; Hairy like; Hairy-like protein; HAIRY1; HES-1; hes1; Hes1 hairy and enhancer of split 1 (Drosophila); HHL; HL; HRY; MGC129109; OTTHUMP00000209031; RHL; Transcription factor HES-1; anti-HES1 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
410 mug/mL (varies by lot)
Sequence Length
282
Applicable Applications for anti-HES1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse HES1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of various samples using HES1 Polyclonal Antibody at dilution of 1:600.)
Western Blot (WB)
(Western Blot analysis of various samples using HES1 Polyclonal Antibody at dilution of 1:600.)
Related Product Information for anti-HES1 antibody
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Product Categories/Family for anti-HES1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 30kDa
Observed: 30kDa
Observed: 30kDa
NCBI Official Full Name
transcription factor HES-1
NCBI Official Synonym Full Names
hes family bHLH transcription factor 1
NCBI Official Symbol
Hes1
NCBI Official Synonym Symbols
Hry; bHLHb39
NCBI Protein Information
transcription factor HES-1
UniProt Protein Name
Transcription factor HES-1
Protein Family
UniProt Gene Name
Hes1
UniProt Synonym Gene Names
Hes-1
Uniprot Description
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage ().
Research Articles on HES1
1. this paper shows that epithelial Hes1 maintains gut homeostasis by preventing microbial dysbiosis
Similar Products
Product Notes
The HES1 hes1 (Catalog #AAA2556273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HES1 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HES1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the HES1 hes1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HES1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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