Rabbit HEI-C Polyclonal Antibody | anti-HEI-C antibody

Anti-HEI-C Antibody

Cat. Num. AAA8306855

• Gene Names: HAUS1; HEIC; CCDC5; HEI-C; HsT1461
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Purified by Immunogen Affinity Chromatography
• Synonyms: HEI-C; Polyclonal Antibody; Anti-HEI-C Antibody; CCDC5; HEIC; HAUS augmin-like complex subunit 1; Coiled-coil domain-containing protein 5; Enhancer of invasion-cluster; anti-HEI-C antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of HEI-C protein.
• Purity/Purification: Purified by Immunogen Affinity Chromatography
• Form/Format: Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.

• Applicable Applications for anti-HEI-C antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human HEI-C. The exact sequence is proprietary.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of HEI-C expression in HeLa (A), mouse testis (B), rat testis (C) whole cell lysates.)

Related Product Information for anti-HEI-C antibody

Rabbit polyclonal antibody to HEI-C

NCBI and Uniprot Product Information

• NCBI GI #: 19923971
• NCBI GeneID: 115106
• NCBI Accession #: NP_612452.1
• NCBI GenBank Nucleotide #: NM_138443.3
• UniProt Accession #: Q96CS2; Q8BHX1; Q9R0A8
• Molecular Weight: 22,744 Da
• NCBI Official Full Name: HAUS augmin-like complex subunit 1
• NCBI Official Synonym Full Names: HAUS augmin-like complex, subunit 1
• NCBI Official Symbol: HAUS1
• NCBI Official Synonym Symbols: HEIC; CCDC5; HEI-C; HsT1461
• NCBI Protein Information: HAUS augmin-like complex subunit 1; coiled-coil domain containing 5 (spindle associated); coiled-coil domain-containing protein 5; enhancer of invasion-cluster
• UniProt Protein Name: HAUS augmin-like complex subunit 1
• UniProt Gene Name: HAUS1
• UniProt Synonym Gene Names: CCDC5; HEIC; HEI-C
• UniProt Entry Name: HAUS1_HUMAN

NCBI Description

HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

Uniprot Description

CCDC5: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS1 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: spindle pole; centrosome; microtubule; cytoplasm

Molecular Function: protein binding

Biological Process: mitosis; cell division; centrosome organization and biogenesis; spindle assembly