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Western Blot (WB) (Western blot analysis of Jurkat cell lysate (lane 1) and mouse small intestine tissue lysate (lane 2) probed with Rabbit anti heat shock protein 90 alpha antibody)

Rabbit anti-Human HEAT SHOCK PROTEIN 90 ALPHA Polyclonal Antibody | anti-HSP90AA1 antibody

RABBIT ANTI HEAT SHOCK PROTEIN 90 ALPHA

Gene Names
HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Synonyms
HEAT SHOCK PROTEIN 90 ALPHA; Polyclonal Antibody; RABBIT ANTI HEAT SHOCK PROTEIN 90 ALPHA; anti-HSP90AA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
HEAT SHOCK PROTEIN 90 ALPHA
Form/Format
Purified IgG - liquid
Concentration
IgG concentration 0.5 mg/ml (varies by lot)
Sequence Length
732
Applicable Applications for anti-HSP90AA1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
Immunohistochemistry- Paraffin: 5 ug/ml
Western Blot: 0.5; 4.0 ug/ml
Reactivity Notes
Mouse, Rat
Preservative Stabilisers
30% Glycerol, 0.5% Bovine Serum Albumin, 0.01% Thiomersal
Buffer Solution
Phosphate buffered saline
Preparation and Storage
Store at -20 degree C Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch

Western Blot (WB)

(Western blot analysis of Jurkat cell lysate (lane 1) and mouse small intestine tissue lysate (lane 2) probed with Rabbit anti heat shock protein 90 alpha antibody)

Western Blot (WB) (Western blot analysis of Jurkat cell lysate (lane 1) and mouse small intestine tissue lysate (lane 2) probed with Rabbit anti heat shock protein 90 alpha antibody)
Related Product Information for anti-HSP90AA1 antibody
Rabbit anti heat shock protein 90 alpha antibody recognizes heat shock protein 90 alpha, also known as lipopolysaccharide-associated protein 2, renal carcinoma antigen NY-REN-38 and HSP86. Heat shock protein 90 alpha is a highly abundant protein. It acts as a molecular chaperone and plays a crucial role in protecting cells against heat induced stress.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
98,161 Da
NCBI Official Full Name
Heat shock protein HSP 90-alpha
NCBI Official Synonym Full Names
heat shock protein 90kDa alpha family class A member 1
NCBI Official Symbol
HSP90AA1
NCBI Official Synonym Symbols
EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p
NCBI Protein Information
heat shock protein HSP 90-alpha
UniProt Protein Name
Heat shock protein HSP 90-alpha
Protein Family
UniProt Gene Name
HSP90AA1
UniProt Synonym Gene Names
HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2
UniProt Entry Name
HS90A_HUMAN

NCBI Description

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11274138, PubMed:11276205, PubMed:15577939, PubMed:15937123, PubMed:27353360).

Research Articles on HSP90AA1

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Product Notes

The HSP90AA1 hsp90aa1 (Catalog #AAA224928) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI HEAT SHOCK PROTEIN 90 ALPHA reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HEAT SHOCK PROTEIN 90 ALPHA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). Immunohistochemistry- Paraffin: 5 ug/ml Western Blot: 0.5; 4.0 ug/ml. Researchers should empirically determine the suitability of the HSP90AA1 hsp90aa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HEAT SHOCK PROTEIN 90 ALPHA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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