Rabbit Heat Shock Protein 70 Interacting Protein Polyclonal Antibody | anti-HSPBP1 antibody
Heat Shock Protein 70 Interacting Protein (HSPBP1, Hsp70 Binding Protein)
Gene Names
HSPBP1; FES1
Applications
Western Blot
Purity
SerumSerum
Synonyms
Heat Shock Protein 70 Interacting Protein; Polyclonal Antibody; Heat Shock Protein 70 Interacting Protein (HSPBP1; Hsp70 Binding Protein); Anti -Heat Shock Protein 70 Interacting Protein (HSPBP1; anti-HSPBP1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Chlamydomonas reinhardtii Dna K.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a lyophilized powder. Reconstitute with 200ul sterile water.
Applicable Applications for anti-HSPBP1 antibody
Western Blot (WB)
Application Notes
Dilution: Western Blot:1:5000
Immunogen
Recombinant Dna K of Chlamydomonas reinhardtii.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-HSPBP1 antibody
The prokaryotic Hsp70 protein family includes DNA K, HSCA (Hsc66), and HscC (Hsc62) (1). DNAK interacts with DNAJ and GrpE heat shock protein chaperones to fold substrate proteins in an ATP-driven cycle (2). These proteins are also involved in cell protection from environmental stress and other functions which are vital for a living cell. And like eukaryotic Hsp70 homologs, DNAK participates in the assembly/disassembly of protein complexes (3, 4).
Product Categories/Family for anti-HSPBP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,474 Da
NCBI Official Full Name
hsp70-binding protein 1
NCBI Official Synonym Full Names
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
NCBI Official Symbol
HSPBP1
NCBI Official Synonym Symbols
FES1
NCBI Protein Information
hsp70-binding protein 1; hspBP2; Hsp70 binding protein 1; hsp70-binding protein 2; hsp70 interacting protein; hsp70-interacting protein 1; hsp70-interacting protein 2; heat shock protein-binding protein 1
UniProt Protein Name
Hsp70-binding protein 1
Protein Family
UniProt Gene Name
HSPBP1
UniProt Synonym Gene Names
HSPBP; HspBP1; HspBP2
UniProt Entry Name
HPBP1_HUMAN
Uniprot Description
HSPBP1: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 19q13.42
Molecular Function: enzyme inhibitor activity; protein binding
Biological Process: protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of catalytic activity
Research Articles on HSPBP1
Similar Products
Product Notes
The HSPBP1 hspbp1 (Catalog #AAA623049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Heat Shock Protein 70 Interacting Protein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Dilution: Western Blot:1:5000. Researchers should empirically determine the suitability of the HSPBP1 hspbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Heat Shock Protein 70 Interacting Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
