Rabbit anti-Human, Mouse HCRTR2 Polyclonal Antibody | anti-HCRTR2 antibody
HCRTR2, ID (HCRTR2, Orexin receptor type 2, Hypocretin receptor type 2) (APC)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(HCRTR2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HCRTR2 antibody detected the HCRTR2 protein (arrow).)
Western Blot (WB)
(HCRTR2 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the HCRTR2 antibody detected the HCRTR2 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
Uniprot Description
HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide hormone binding; peptide binding
Biological Process: synaptic transmission; neuropeptide signaling pathway; circadian sleep/wake cycle process; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cellular response to hormone stimulus; regulation of circadian sleep/wake cycle, sleep
Research Articles on HCRTR2
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Product Notes
The HCRTR2 hcrtr2 (Catalog #AAA6305835) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HCRTR2, ID (HCRTR2, Orexin receptor type 2, Hypocretin receptor type 2) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's HCRTR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HCRTR2 hcrtr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCRTR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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