Rabbit H6PD Polyclonal Antibody | anti-H6PD antibody

H6PD Rabbit Polyclonal

Cat. Num. AAA769973

• Gene Names: H6pd; Gpd1; G6pd1; Gpd-1; AI785303
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry, Western Blot, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: H6PD; Polyclonal Antibody; H6PD Rabbit Polyclonal; anti-H6PD antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 789

• Applicable Applications for anti-H6PD antibody: ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
• Immunogen: Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat kidney using MBS769973 (H6PD antibody) at dilution of 1:100)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS769973 (H6PD Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 27503677
• NCBI GeneID: 100198
• Molecular Weight: 88,928 Da
• NCBI Official Full Name: H6pd protein
• NCBI Official Synonym Full Names: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
• NCBI Official Symbol: H6pd
• NCBI Official Synonym Symbols: Gpd1; G6pd1; Gpd-1; AI785303
• NCBI Protein Information: GDH/6PGL endoplasmic bifunctional protein
• UniProt Protein Name: GDH/6PGL endoplasmic bifunctional protein
• Protein Family: GDH/6PGL endoplasmic bifunctional protein
• UniProt Gene Name: H6pd
• UniProt Synonym Gene Names: 6PGL
• UniProt Entry Name: G6PE_MOUSE

Uniprot Description

H6PD: Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates. Defects in H6PD are a cause of cortisone reductase deficiency (CRD). In CRD, activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype resembling polycystic ovary syndrome (PCOS).

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 3.1.1.31; EC 1.1.1.47; Hydrolase; Oxidoreductase

Cellular Component: cytoplasm; endoplasmic reticulum; intracellular membrane-bound organelle; mitochondrion

Molecular Function: 6-phosphogluconolactonase activity; carbohydrate binding; catalytic activity; glucose 1-dehydrogenase activity; glucose-6-phosphate dehydrogenase activity; hydrolase activity; NADP binding; oxidoreductase activity

Biological Process: carbohydrate metabolic process; glucose metabolic process; metabolic process; NADP metabolic process; pentose-phosphate shunt