Rabbit Guanine nucleotide binding protein, beta 5 Subunit Polyclonal Antibody | anti-Gbeta5 antibody
Guanine nucleotide binding protein, beta 5 Subunit (Gbeta5, FLJ37457, FLJ43714, GB5, Gbeta5, Guanine nucleotide-binding protein subunit beta-5, Transducin beta Chain 5) (FITC)
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western Blot Analysis: L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-G protein Gbeta5 (1:500 dilution of this lot). Proteins were visualized using a donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates G protein Gbeta5 (~40kD).)
NCBI and Uniprot Product Information
NCBI Description
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
Uniprot Description
G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, heterotrimeric beta
Chromosomal Location of Human Ortholog: 15q21.2
Cellular Component: plasma membrane; nucleus
Molecular Function: GTPase activity; G-protein gamma-subunit binding; protein binding; signal transducer activity; chaperone binding
Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction
Research Articles on Gbeta5
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Product Notes
The Gbeta5 gnb5 (Catalog #AAA6479279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Guanine nucleotide binding protein, beta 5 Subunit (Gbeta5, FLJ37457, FLJ43714, GB5, Gbeta5, Guanine nucleotide-binding protein subunit beta-5, Transducin beta Chain 5) (FITC) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Guanine nucleotide binding protein, beta 5 Subunit can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Gbeta5 gnb5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Guanine nucleotide binding protein, beta 5 Subunit, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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