Rabbit anti-Human GTPBP10 Polyclonal Antibody | anti-GTPBP10 antibody

GTPBP10 Antibody

Cat. Num. AAA9631183

• Gene Names: GTPBP10; ObgH2; UG0751c10
• Reactivity: Human
• Applications: ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Synonyms: GTPBP10; Polyclonal Antibody; GTPBP10 Antibody; BC034507; Claudin 12; Cldn12; FLJ38242; GTP binding protein 10 (putative); GTP-binding protein 10; GTPBA_HUMAN; MGC104191; MGC30495; ObgH2; Protein obg homolog 2; anti-GTPBP10 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: GTPBP10 Antibody detects endogenous levels of GTPBP10.
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Form/Format: Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-GTPBP10 antibody: ELISA (EIA)(peptide)
• Application Notes: ELISA(peptide): 1:20000-1:40000
• Immunogen: A synthesized peptide derived from human GTPBP10.
• Conjugation: Unconjugated
• Similarity: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
• Function: May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed.
• Note: Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase. Gradually re-assembles into the nucleolus at late anaphase to telophase.
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Product Categories/Family for anti-GTPBP10 antibody

Nucleus; Chromosome; Primary

NCBI and Uniprot Product Information

• NCBI GI #: 48257234
• NCBI GeneID: 85865
• UniProt Accession #: A4D1E9; Q3B7A6; Q5H9V2; Q8IXG8; Q8N982; Q8WU16; Q9BSP1; Q9Y6T6; B4DFY6
• Molecular Weight: 42,933 Da
• NCBI Official Full Name: GTPBP10 protein
• NCBI Official Synonym Full Names: GTP-binding protein 10 (putative)
• NCBI Official Symbol: GTPBP10
• NCBI Official Synonym Symbols: ObgH2; UG0751c10
• NCBI Protein Information: GTP-binding protein 10; protein obg homolog 2
• UniProt Protein Name: GTP-binding protein 10
• Protein Family: GTP-binding protein
• UniProt Gene Name: GTPBP10
• UniProt Synonym Gene Names: OBGH2; ObgH2
• UniProt Entry Name: GTPBA_HUMAN

NCBI Description

Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]

Uniprot Description

GTPBP10: May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed. Belongs to the GTP1/OBG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 7q21.13

Cellular Component: mitochondrion; nucleolus; chromosome

Molecular Function: GTPase activity; GTP binding; magnesium ion binding

Biological Process: metabolic process; ribosome biogenesis and assembly