Western Blot (WB)
(WB Suggested Anti-GTF2A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:500Positive Control: Human Muscle)
Rabbit GTF2A1 Polyclonal Antibody | anti-GTF2A1 antibody
GTF2A1 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-GTF2A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:500Positive Control: Human Muscle)
Western Blot (WB)
(WB Suggested Anti-GTF2A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:500Positive Control: Human Muscle)
Target Description: Transcription initiation factor IIA . and . chains (GTF2A1, TFIIA p35 and p19 subunits, TFIIAL) binding ability of TLP is required for characteristic cytoplasmic localization of TLP. TFIIA may regulate the intracellular molecular state and the function of TLP through its property of binding to TLP.
NCBI and Uniprot Product Information
NCBI Description
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
Uniprot Description
GTF2A1: a general transcription factor that plays an important role in transcriptional activation. A component of the transcription machinery of RNA polymerase II. Phosphorylated by Taf(II) 250 on serines that regulate TBP binding. Interacts with TBP (the TATA-binding protein). Two isoforms, 42 kDa and 37 kDa, are produced by alternative initiation.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 14q31.1
Cellular Component: nucleoplasm; cytoplasm; transcription factor TFIIA complex
Molecular Function: protein binding; DNA binding; TATA-binding protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; viral reproduction; RNA elongation from RNA polymerase II promoter; gene expression
Research Articles on GTF2A1
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Product Notes
The GTF2A1 gtf2a1 (Catalog #AAA3200389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GTF2A1 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's GTF2A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GTF2A1 gtf2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: QAPLVLQVDG TGDTSSEEDE DEEEDYDDDE EEDKEKDGAE DGQVEEEPLN. It is sometimes possible for the material contained within the vial of "GTF2A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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