Rabbit GSTA1 Polyclonal Antibody | anti-GSTA1 antibody

GSTA1 Rabbit Polyclonal

Cat. Num. AAA769918

• Gene Names: GSTA1; GST2; GTH1; GSTA1-1; GST-epsilon
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: GSTA1; Polyclonal Antibody; GSTA1 Rabbit Polyclonal; anti-GSTA1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 129

• Applicable Applications for anti-GSTA1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
• Immunogen: Glutathione S-transferase alpha 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS769918 (GSTA1 antibody) at dilution of 1:50)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells, using MBS769918 (GSTA1 antibody) at 1:25 dilution)

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS769918 (GSTA1 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 975830176
• NCBI GeneID: 2938
• NCBI Accession #: NP_001305988.1
• NCBI GenBank Nucleotide #: NM_001319059.1
• Molecular Weight: 25,631 Da
• NCBI Official Full Name: glutathione S-transferase A1 isoform 2
• NCBI Official Synonym Full Names: glutathione S-transferase alpha 1
• NCBI Official Symbol: GSTA1
• NCBI Official Synonym Symbols: GST2; GTH1; GSTA1-1; GST-epsilon
• NCBI Protein Information: glutathione S-transferase A1
• UniProt Protein Name: Glutathione S-transferase A1
• Protein Family: Glutathione S-transferase
• UniProt Gene Name: GSTA1
• UniProt Entry Name: GSTA1_HUMAN

NCBI Description

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Uniprot Description

GSTA1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Alpha family.

Protein type: Transferase; Other Amino Acids Metabolism - glutathione; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: cytosol

Molecular Function: glutathione transferase activity

Biological Process: epithelial cell differentiation; glutathione metabolic process; metabolic process