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Rabbit GRASP Polyclonal Antibody | anti-GRASP antibody

GRASP Antibody

Gene Names
GRASP; TAMALIN
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
GRASP; Polyclonal Antibody; GRASP Antibody; General receptor for phosphoinositides 1-associated scaffold protein; Grasp; GRASP_HUMAN; GRP1 (general receptor for phosphoinositides 1) associated scaffold protein; GRP1 associated scaffold protein; GRP1-associated scaffold protein; Tamalin; anti-GRASP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
GRASP Antibody detects endogenous levels of GRASP.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-GRASP antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human GRASP.
Conjugation
Unconjugated
Subunit Structure
Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5 (By similarity).
Function
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
Note
Localized at postsynaptic membranes.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,904 Da
NCBI Official Full Name
general receptor for phosphoinositides 1-associated scaffold protein isoform 2
NCBI Official Synonym Full Names
general receptor for phosphoinositides 1 associated scaffold protein
NCBI Official Symbol
GRASP
NCBI Official Synonym Symbols
TAMALIN
NCBI Protein Information
general receptor for phosphoinositides 1-associated scaffold protein
UniProt Protein Name
General receptor for phosphoinositides 1-associated scaffold protein
Protein Family
UniProt Gene Name
GRASP
UniProt Synonym Gene Names
GRP1-associated scaffold protein

NCBI Description

This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]

Uniprot Description

GRASP: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: plasma membrane

Biological Process: signal transduction

Research Articles on GRASP

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Product Notes

The GRASP grasp (Catalog #AAA9630893) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRASP Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GRASP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the GRASP grasp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRASP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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