Testing Data
Rabbit GRAF Polyclonal Antibody | anti-GRAF antibody
GRAF Polyclonal Antibody
Gene Names
ARHGAP26; GRAF; GRAF1; OPHN1L; OPHN1L1
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
GRAF; Polyclonal Antibody; GRAF Polyclonal Antibody; arhgap 26; ARHGAP26; FLJ42530; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); KIAA0621; oligophrenin 1 like protein; Oligophrenin-1-like protein; oligophrenin1like protein; OPHN1L; OPHN1L1; RHG26_HUMAN; Rho GTPase activating protein 26; Rho GTPase activating protein26; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26; anti-GRAF antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
Clonality
Polyclonal
Specificity
GRAF Polyclonal Antibody detects endogenous levels of GRAF protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-GRAF antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human GRAF1
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-GRAF antibody
Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,165 Da
NCBI Official Full Name
rho GTPase-activating protein 26 isoform b
NCBI Official Synonym Full Names
Rho GTPase activating protein 26
NCBI Official Symbol
ARHGAP26
NCBI Official Synonym Symbols
GRAF; GRAF1; OPHN1L; OPHN1L1
NCBI Protein Information
rho GTPase-activating protein 26; GTPase regulator associated with focal adhesion kinase pp125(FAK); oligophrenin-1-like protein
UniProt Protein Name
Rho GTPase-activating protein 26
UniProt Gene Name
ARHGAP26
UniProt Synonym Gene Names
GRAF; KIAA0621; OPHN1L
UniProt Entry Name
RHG26_HUMAN
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Product Notes
The GRAF arhgap26 (Catalog #AAA3015212) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRAF Polyclonal Antibody reacts with Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's GRAF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the GRAF arhgap26 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRAF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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